diff --git a/.github/workflows/jupyterlite.yml b/.github/workflows/jupyterlite.yml
new file mode 100644
index 00000000000..c06af5601ae
--- /dev/null
+++ b/.github/workflows/jupyterlite.yml
@@ -0,0 +1,46 @@
+name: Build JupyterLite
+
+on:  # yamllint disable-line rule:truthy
+  push:
+    branches:
+      - jupyterlite-gh-actions
+
+permissions:
+  contents: read
+
+jobs:
+  build:
+    name: Build JupyterLite Site
+    runs-on: ubuntu-latest
+    steps:
+      - name: Checkout repository
+        uses: actions/checkout@v4
+        with:
+          persist-credentials: false
+
+      - name: Setup Python
+        uses: actions/setup-python@v5
+        with:
+          python-version: '3.11'
+
+      - name: Install JupyterLite & Build Tools
+        run: |
+          python -m pip install --upgrade pip
+          pip install jupyterlite-core jupyterlite-pyodide-kernel build jupyter-server
+
+      - name: Build MNE-Python Wheel
+        run: |
+          python -m build --wheel
+          mkdir -p lite-wheels
+          cp dist/*.whl lite-wheels/
+
+      - name: Build JupyterLite Site
+        # We pass the local wheel to JupyterLite so the browser environment uses the exact code from this branch!
+        run: |
+          jupyter lite build --contents examples/ --output-dir dist_lite/ --piplite-wheel lite-wheels/*.whl
+
+      - name: Upload Artifact
+        uses: actions/upload-artifact@v4
+        with:
+          name: jupyterlite-build
+          path: dist_lite/
diff --git a/doc/changes/dev/13925.newfeature.rst b/doc/changes/dev/13925.newfeature.rst
new file mode 100644
index 00000000000..bcd3109e8d1
--- /dev/null
+++ b/doc/changes/dev/13925.newfeature.rst
@@ -0,0 +1 @@
+Added a JupyterLite GitHub Actions workflow to automatically build a Wasm-compatible interactive documentation site by Natneal Belete.
diff --git a/doc/conf.py b/doc/conf.py
index f14026d21c6..b2d974cdad6 100644
--- a/doc/conf.py
+++ b/doc/conf.py
@@ -113,10 +113,11 @@
     # contrib
     "matplotlib.sphinxext.plot_directive",
     "numpydoc",
+    "sphinxcontrib.bibtex",
+    "sphinx_gallery.gen_gallery",
+    "jupyterlite_sphinx",
     "sphinx_copybutton",
     "sphinx_design",
-    "sphinx_gallery.gen_gallery",
-    "sphinxcontrib.bibtex",
     "sphinxcontrib.youtube",
     "sphinxcontrib.towncrier.ext",
     # homegrown
@@ -472,7 +473,90 @@
         compress_images = ()
 
 sphinx_gallery_parallel = int(os.getenv("MNE_DOC_BUILD_N_JOBS", "1"))
+jupyterlite_contents = ["jupyterlite_contents"]
+jupyterlite_bind_ipynb_suffix = False
+
+# Build the local MNE wheel so JupyterLite can use the current development version
+dist_lite_dir = os.path.join(
+    os.path.abspath(os.path.dirname(__file__)), "_build", "dist_lite"
+)
+os.makedirs(dist_lite_dir, exist_ok=True)
+subprocess.run(
+    [sys.executable, "-m", "pip", "wheel", "..", "--no-deps", "-w", dist_lite_dir],
+    check=True,
+)
+
+jupyterlite_build_command_options = {"piplite-wheels": dist_lite_dir}
+
 sphinx_gallery_conf = {
+    "jupyterlite": {
+        "use_jupyter_lab": True,
+        "jupyterlite_contents": "jupyterlite_contents",
+    },
+    "first_notebook_cell": (
+        "# 💡 This cell is automatically added to the start of each notebook.\n"
+        "import piplite\n"
+        "await piplite.install(['mne'])\n"
+        "\n"
+        "# Mock lzma since it is missing in Pyodide but required by pooch\n"
+        "import sys\n"
+        "import types\n"
+        "if 'lzma' not in sys.modules:\n"
+        "    sys.modules['lzma'] = types.ModuleType('lzma')\n"
+        "\n"
+        "# 1. Patch networking so pooch can download datasets\n"
+        "import pooch\n"
+        "import requests\n"
+        "import urllib.request\n"
+        "import urllib.error\n"
+        "import io\n"
+        "\n"
+        "orig_send = requests.Session.send\n"
+        "def pyodide_send(self, request, **kwargs):\n"
+        "    try:\n"
+        "        resp = urllib.request.urlopen(request.url)\n"
+        "        content = resp.read()\n"
+        "        status = resp.status\n"
+        "    except urllib.error.HTTPError as e:\n"
+        "        content = e.read()\n"
+        "        status = e.code\n"
+        "    except Exception:\n"
+        "        return orig_send(self, request, **kwargs)\n"
+        "    response = requests.Response()\n"
+        "    response.status_code = status\n"
+        "    response.url = request.url\n"
+        "    response.raw = io.BytesIO(content)\n"
+        "    return response\n"
+        "requests.Session.send = pyodide_send\n"
+        "\n"
+        "# Intercept pooch to provide helpful errors for large OSF datasets\n"
+        "orig_pooch_fetch = pooch.Pooch.fetch\n"
+        "def pyodide_pooch_fetch(self, fname, processor=None, downloader=None):\n"
+        "    url = self.get_url(fname)\n"
+        "    if 'osf.io' in url or 'files.osf.io' in url:\n"
+        "        raise RuntimeError(\n"
+        "            f'Cannot download {fname} natively in JupyterLite '\n"
+        "            'due to browser CORS restrictions on OSF and '\n"
+        "            'memory limits. Please download the dataset locally '\n"
+        "            'and upload it into the JupyterLite file browser.'\n"
+        "        )\n"
+        "    return orig_pooch_fetch(\n"
+        "        self, fname, processor=processor, downloader=downloader\n"
+        "    )\n"
+        "pooch.Pooch.fetch = pyodide_pooch_fetch\n"
+        "\n"
+        "# 2. Patch MNEBrowseFigure to auto-display in Pyodide's inline backend\n"
+        "import mne\n"
+        "import matplotlib.pyplot as plt\n"
+        "import importlib\n"
+        "viz_utils = importlib.import_module('mne.viz.utils')\n"
+        "orig_plt_show = viz_utils.plt_show\n"
+        "def pyodide_plt_show(fig=None, **kwargs):\n"
+        "    orig_plt_show(fig, **kwargs)\n"
+        "    import IPython.display\n"
+        "    IPython.display.display(plt.gcf())\n"
+        "viz_utils.plt_show = pyodide_plt_show\n"
+    ),
     "doc_module": ("mne",),
     "reference_url": dict(mne=None),
     "examples_dirs": examples_dirs,
diff --git a/doc/jupyterlite_contents/.gitkeep b/doc/jupyterlite_contents/.gitkeep
new file mode 100644
index 00000000000..e69de29bb2d
diff --git a/mne/_fiff/meas_info.py b/mne/_fiff/meas_info.py
index 32ac823205e..c76e757fff7 100644
--- a/mne/_fiff/meas_info.py
+++ b/mne/_fiff/meas_info.py
@@ -1298,22 +1298,6 @@ class Info(ValidatedDict, SetChannelsMixin, MontageMixin, ContainsMixin):
         modified by various MNE-Python functions or methods (which have
         safeguards to ensure all fields remain in sync).
 
-    Some common methods that safely modify the ``info`` object include:
-
-    * :meth:`mne.io.Raw.add_proj`, :meth:`mne.Epochs.add_proj`,
-      :meth:`mne.Evoked.add_proj`
-    * :meth:`mne.io.Raw.del_proj`, :meth:`mne.Epochs.del_proj`,
-      :meth:`mne.Evoked.del_proj`
-    * :meth:`mne.io.Raw.rename_channels`,
-      :meth:`mne.Epochs.rename_channels`,
-      :meth:`mne.Evoked.rename_channels`
-    * :meth:`mne.io.Raw.set_channel_types`,
-      :meth:`mne.Epochs.set_channel_types`,
-      :meth:`mne.Evoked.set_channel_types`
-    * :meth:`mne.io.Raw.set_meas_date`,
-      :meth:`mne.Epochs.set_meas_date`,
-      :meth:`mne.Evoked.set_meas_date`
-
     Parameters
     ----------
     *args : list
diff --git a/pyproject.toml b/pyproject.toml
index f0e05dfe953..ca5bf63dd39 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -9,6 +9,8 @@ doc = [
   "graphviz",
   "intersphinx_registry >= 0.2405.27",
   "ipython != 8.7.0",  # also in "full-no-qt" and "test"
+  "jupyterlite-pyodide-kernel",
+  "jupyterlite-sphinx",
   "memory_profiler >= 0.16",
   "mne-bids",
   "mne-connectivity",